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Anti-EGFR agents detrimental in colorectal cancer patients with KRAS mutation

from Medscape Medical News

For the second time in a major clinical study, patients with colorectal cancer whose tumors contain the mutant form of the KRAS gene have shown negative outcomes when treated with an antiepidermal growth factor receptor (EGFR). It is already well established that only patients with wild-type KRAS tumors benefit from treatment with an anti-EGFR agent and that patients with KRAS mutations do not. more


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