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S100A1 expression in ovarian and endometrial endometrioid carcinomas is a prognostic indicator of relapse-free survival

from the American Society for Clinical Pathology

We sought to investigate the expression levels of S100A1 in ovarian cancer cell lines and tissues to correlate S100A1 with subtype, stage, grade, and relapse-free survival. S100A1 messenger RNA and protein were up-regulated in ovarian cancer cell lines and tumors compared with normal ovarian cell lines and tissues by gene microarray analysis, reverse transcriptase–polymerase chain reaction, quantitative reverse transcriptase–polymerase chain reaction, and Western immunoblotting. more


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