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Gene variants associated with susceptibility to postsurgical chronic pain

from Medscape Medical News

A new study has found associations between variants of the gene CACNG2 and patients' experiences of chronic pain after breast cancer surgery. The gene was previously known to encode stargazin, a protein involved in alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)-type glutamate receptors, and a possible subunit of calcium channels implicated in epilepsy. The present findings contribute information about the physiology of neuropathic pain and its potential treatment. more

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