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Function found for protein that causes Alzheimer's disease

from Daily News & Analysis

Researchers have found a function for the amyloid precursor protein that yields the prime ingredient in amyloid plaques, which lead to Alzheimer's disease. It turns out that APP is an iron oxidase whose job it is to convert iron from an unsafe form to a safe one for transport or storage. When APP fails to function properly, as it does in Alzheimer's disease, iron levels inside neurons mount to toxic levels. more

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