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Science & Research Update: Salivary Glands May Offer New Route to Immunity

New research suggests that vaccinations delivered through salivary glands may provide protection against a wide array of diseases, according to the Federation of American Societies for Experimental Biology (FASEB) who announced these findings last month in their FASEB Journal. ACSM is a member organization of FASEB.

Researchers studied two groups of mice – one that received live cytomegalovirus directly into their salivary glands and one that received an inactive virus. The former demonstrated an immune response while the latter did not. When both groups were later exposed to the virus, only the group immunized with the active virus was protected from future infection. Researchers believe salivary glands may become the first line of defense in active and passive immunization, and they hope, in the future, salivary gland inoculation becomes a clinically acceptable method in which to vaccinate individuals against diseases ranging from influenza to cholera. Learn more about the study. more

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