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High-dose statins may increase diabetes risk

from WebMD

The strongest doses of cholesterol-lowering statin medications prevent heart attacks and strokes in patients with cardiovascular disease, but they may also modestly increase the risk of developing type 2 diabetes, a new study shows. The study, a reanalysis of five clinical trials representing nearly 33,000 patients, found that the risk of developing type 2 diabetes increased slightly in patients who were on the most aggressive statin regimens compared to those on less powerful statin doses. For every 498 patients who took high-dose statins for one year, there was one extra case of diabetes. At the same time, however, the medications prevented one cardiovascular event such as a heart attack or stroke for every 155 people who took them. more


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