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Studying protein folding with fluorescence detection


By combining a spectrograph, a lamp-based fluorescence detector and capillary electrophoresis, a team of Dutch pharmaceutical scientists are able to study protein folding in two complementary but entirely different ways. As well as revealing more information about how proteins fold and unfold, this technique could help pharmaceutical companies monitor the quality of their therapeutic proteins and offer a new way to study the many diseases caused by misfolded proteins, such as Alzheimer's disease. more

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