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Study uncovers recurrent gene fusion in colorectal cancer

from ADVANCE Healthcare

Researchers from the U.S., Israel and Spain have identified a recurrent gene fusion that turns up in some colorectal cancers. Investigators sequenced the genomes of nine colorectal tumors and matched normal tissue samples, identifying a few dozen genes that harbor possibly deleterious substitutions, small insertions or deletions in two or more tumor genomes, along with 11 rearrangements predicted to produce fusion proteins, as reported in Nature Genetics online. more

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