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GIFT exome analysis unearths 2 new genes related to platelet function

from Heartwire via Medscape

The first whole exome analysis of the genome of almost 150 white patients taking part in the GRAVITAS trial has revealed two new genes that appear to be critical to platelet function. "CYP2C19*2 only explains a small portion of the overall variability in the clopidogrel response," Dr. Matthew Price. "So the question is, can we find other markers that further explain the variability? And therefore have a comprehensive genetic panel, so we can make better decisions before the procedure about which antiplatelet therapy to use?" more

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