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Gene mutations vary in familial polyposis

from MedPage Today

The prevalence of two gene mutations in patients with colorectal polyps varied widely according to the number of adenomas present, a cross-sectional study indicated. Among 119 patients who had the highest number of adenomas — 1,000 or more — 80 percent had a mutation in the APC gene while only 2 percent had mutations in the MUTYH gene, researchers said. more

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