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Active Voice: Exercise Speeds Healing in Obese Mice

from By Brandt Pence, Ph.D. and Jeffrey Woods, Ph.D., FACSM

Viewpoints presented in SMB commentaries reflect opinions of the authors and do not necessarily reflect positions or policies of ACSM.

Brandt Pence, Ph.D., is a postdoctoral researcher in the Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign. He is a member of ACSM, with research interests in the broad area of exercise, obesity, and immune function, including defects in wound healing and impairments in anti-viral immunity associated with the obese state.

Jeffrey Woods, Ph.D., FACSM, is a professor of exercise physiology in the Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign. His research career has been focused on the impact of exercise on immune function in conditions as diverse as obesity, normal aging, cancer and infection. His current research is focused on the neuroimmunological and behavioral impacts of exercise and nutrition during the aging process.

The following commentary reflects Dr. Pence’s and Dr. Woods’ views relating to their and colleagues’ research article, which appears in the October 2012 issue of Medicine and Science in Sports and Exercise®, “Exercise Speeds Cutaneous Wound Healing in High-Fat Diet-Induced Obese Mice.”


Obesity has become a nationwide (and indeed worldwide) concern, with recent estimates of more than two-thirds of adults in the United States being classified as overweight or obese. Obesity, while itself a concern, also brings with it a large number of related problems. From recent evidence of impaired immune responses to influenza H1N1/09 (the “swine flu”) in individuals with obesity, to the more well-known relationship between obesity and type 2 diabetes, comorbidities associated with obesity create a great strain on healthcare systems in the United States and around the world. more


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