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Cyclosporine versus everolimus: Effects on the glomerulus

from Clinical Transplantation (login required)

Inhibitors of the mammalian target of rapamycin (mTOR) have been associated with proteinuria. In a recent study, researchers studied the development of proteinuria in renal transplant recipients (RTR) treated with the mTOR inhibitor everolimus in comparison with a calcineurin inhibitor. They related the presence of proteinuria to histopathological glomerular findings in two-year protocol biopsies. more


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