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Research casts doubt on Parkinson's disease treatment

from Chicago Tribune

A recent study questions long-held assumptions about the way a brain protein affects the progression of Parkinson's disease. Researchers in 1997 linked Parkinson's with the protein alpha-synuclein. They began looking for ways to block it to slow the progression of the disease, which is characterized by such symptoms as tremors, rigidity, trouble walking and slowness of movement and affects more than a million Americans. Demetrius Maraganore, a neurologist at NorthShore University HealthSystem in Evanston, has been working with Mayo Clinic researchers to study that brain protein, focusing on its relationship to two key effects of Parkinson's disease: motor and cognitive impairment and dementia. more


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