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Proximity ligation assays: Advancing the study of proteins

from By Dr. Afsaneh Motamed-Khorasani

Proximity ligation assay, or PLA, is a novel method for the detection of proteins, post-translational modification of proteins and protein-protein interactions. This method will play a key role in future diagnostics and makes it possible to study the presence of the less abundant proteins, and thus it will be easier to identify relevant diseases. Multiplex assays could be designed in which many proteins in the same sample are detected using PLA. more

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