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Evidence mounts for endometrial cancer tumor testing to identify women with Lynch Syndrome

from ScienceDaily

A recent article by Norris Cotton Cancer Center researchers published in the January 2014 issue of the journal Clinical Chemistry reviews the scientific evidence that warrants screening all endometrial cancers for Lynch syndrome. Next to colorectal cancer, endometrial cancer is the most common form of cancer in women with Lynch syndrome. Currently at Dartmouth-Hitchcock Medical Center, every colon cancer specimen is screened for Lynch syndrome via specialized tumor testing. There is mounting evidence that this special tumor testing should also be done on every endometrial cancer specimen. This tumor testing, known as immunohistochemistry and microsatellite instability, gives clinicians some preliminary information to see if Lynch syndrome played a role in the development of their patient's cancer. more

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