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Scientists identify genetic flaw that drives some ovarian cancers

from Health Canal

Researchers at Dana-Farber Cancer Institute have identified an overactive gene that drives about one-third of high-grade serous ovarian tumors — the most common and malignant type of ovarian cancer. The gene, GAB2, isn't mutated or abnormal, but triggers cancerous cell growth because the gene has been amplified — excessive copies of it are present in the cancer cells, the scientists report in the Proceedings of the National Academy of Sciences. more

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