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Two proposed Alzheimer's drugs show disappointing results

from The Los Angeles Times

Two biological therapies designed to improve the clearance of sticky plaques from the brains of those with Alzheimer's disease have failed to slow the steady loss of cognitive function in patients with mild to moderate forms of the degenerative disorder. In late clinical-trial findings published in the New England Journal of Medicine, the monoclonal antibodies known as solanezumab and bapineuzumab were shown ineffective at changing the downward cognitive trajectory of Alzheimer's patients. more


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