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Quadrivalent HPV vaccine effective in women with HIV

from Infectious Disease News

The quadrivalent HPV vaccine was safe and immunogenic among women aged 13 to 45 years with HIV, according to data published in Clinical Infectious Diseases. There was lower seroconversion among women with higher viral loads and/or lower CD4 counts. “HIV-infected women carry a disproportionate burden of HPV-associated diseases,” Erna Milunka Kojic, M.D., said. “Many have already been exposed to HPV infection and overall vaccine responses can be diminished with higher degrees of immunosuppression. Only 4 percent of the women in this cohort had been exposed to all four HPV types in the vaccine as measured by serum antibody titers, so the vast majority of HIV-infected women would likely benefit from receiving the vaccine.” more

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