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Non-myeloablative allogeneic HSCT shows promise for adults with sickle cell disease

from Healio

Adults with sickle cell phenotype achieved a high rate of stable mixed-donor chimerism and disease reversal after they underwent non-myeloablative human leukocyte antigen-matched sibling allogeneic hematopoietic stem cell transplantation, according to study results. Researchers observed the benefits in patients with or without thalassemia. The analysis included 30 patients with severe sickle cell disease. more

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