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New insights into the survival and transmission strategy of malaria parasites

from Swiss Tropical and Public Health Institute via Infection Control Today

HP1 proteins are found in most eukaryotic organisms and are important regulators of gene silencing. In short, HP1 induces heritable condensation of chromosomal regions. As a result, genes located within these regions are not expressed. Importantly, since this conformation is reversible, HP1-controlled genes can become activated without requiring changes in the underlying DNA sequence. more


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