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Fusion of CTLA-4 with HPV16 E7 and E6 enhanced potency of therapeutic HPV DNA vaccine

from PLOS One

Using CTLA-4 with E7 and E6 can enhance cellular and humoral immune responses against HPV16, according to a study published Sept. 29 in PLOS One. This strategy may provide useful ideas for developing therapeutic HPV DNA vaccines. However, further studies are needed to optimize the strategy. more

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