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The cellular origin of fibrosis: Team identifies rare stem cells that give rise to chronic tissue scarring

from Harvard University via Medical Xpress

Harvard Stem Cell Institute scientists at Brigham and Women's Hospital have found the cellular origin of the tissue scarring caused by organ damage associated with diabetes, lung disease, high blood pressure, kidney disease and other conditions. The buildup of scar tissue is known as fibrosis. Fibrosis has a number of consequences, including inflammation and reduced blood and oxygen delivery to the organ. In the long term, the scar tissue can lead to organ failure and eventually death. It is estimated that fibrosis contributes to 45 percent of all deaths in the developed world. more

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