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Colposcopic cervical biopsies: More is usually better

from Medscape (Free login required)

Many clinicians take only one ectocervical biopsy at the time of colposcopy. Recent reports provide good-quality data to guide us regarding the number of biopsies we should perform to best detect high-grade cervical pathology requiring treatment. One report published in late 2014 focused on the value of a single, random cervical biopsy when colposcopy was performed for abnormal cytology, high-risk HPV, or both, but did not reveal cervical lesions. Among almost 2800 such women, biopsy was normal in 90 percent, revealed CIN1 in 6 percent, and CIN2 or worse in 3 percent. more

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