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A new understanding of Alzheimer's

from Harvard Gazette

Although natural selection is often thought of as a force that determines the adaptation of replicating organisms to their environment, Harvard researchers have found that selection also occurs at the level of neurons, which are post-mitotic cells, and plays a critical role in the emergence of Alzheimer's disease. Using the principles of natural selection, Lloyd Demetrius, a researcher in population genetics at Harvard's Museum of Comparative Zoology, and Jane Driver, an assistant professor of medicine at Harvard Medical School, have proposed a new model of Alzheimer's that suggests mitochondria — cellular power plants — might be at the center of the disease. more


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