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Different strokes for different folks: concordance and discordance in anti-hla antibody testing

from Human Immunolgoy

Correct identification of the specificity of antibodies directed against HLA using Single Antigen Luminex Beads (SALB) is essential in current HLA laboratory practice for transplantation. The cumulative data collected by the Proficiency Testing (PT) Program from hundreds of laboratory submissions over years of activity provide an invaluable opportunity to study concordance in antibody testing in a broad group of HLA laboratories. The aim of this study was to investigate the magnitude of concordance and discordance among laboratories in testing for anti-HLA antibodies using SALB. more

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