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POPs and gut microbiota: Dietary exposure alters ratio of bacterial species

from Environmental Health Perspectives

Persistent organic pollutants have been implicated in myriad human health problems, including cancer, neurologic, immunologic and reproductive defects, among many other adverse health effects. New lines of research suggest that chronic dietary exposure to POPs may also contribute to obesity and type 2 diabetes. In this issue of EHP, researchers examine how one POP in particular — 2,3,7,8 tetrachlorodibenzofuran (TCDF) — affects the composition of the mouse gut microbiome. They report that TCDF exposure alters the gut microbiome in ways that may prove to contribute to obesity and other metabolic diseases. more


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