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Primary graft dysfunction and mortality following lung transplantation: A role for proadrenomedullin plasma levels

from American Journal of Transplantation (login required)

Primary graft dysfunction (PGD) after lung transplantation (LT) is a heterogeneous syndrome that comprises clinical presentations with diverse grades of severity. Proadrenomedullin (proADM) levels may be associated with PGD and may enhance its relationship with outcomes. We prospectively included 100 LT recipients. Plasma levels of proADM were measured at 24, 48 and 72 h after admission to the intensive care unit (ICU). We assessed their relationship with PGD grade and ICU mortality. Fifty patients (50 percent) presented grade 3 PGD at ICU admission. more

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