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New finding offers clues for blocking cancer gene

from University of Michigan Health System via Medical Xpress

A new study suggests a potential new way to block one of the most common cancer-causing genes, without causing severe side effects. The Notch gene plays a role in many types of cancer. It's the most common cancer-causing gene in T-cell acute lymphoblastic leukemia. About 60 percent of children and adults with T-cell leukemia harbor a Notch mutation. But drugs designed to block Notch have caused serious side effects such as severe diarrhea or skin cancers. more

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