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Comparing 10-year renal outcomes in deceased donor and living donor liver transplants

from Clinical Trasnplantation (login required)

Few studies have explored whether the type of LT, deceased donor LT (DDLT) or living donor LT (LDLT), impacts long-term renal outcomes. We performed a retrospective analysis of 220 LT recipients at our institution to study their renal outcomes at 10 year. Exclusion criteria were age ≤ 18 year, graft survival ≥ 6 months, and multiorgan transplants; 108 DDLTs and 62 LDLTs were eligible. At baseline, DDLTs had a lower eGFR than LDLTs and 10.2 percent of DDLTs were on dialysis as compared to 0 percent of LDLTs. At 10 year, seven DDLT and three LDLT recipients required dialysis or renal transplant (p = 0.75). In recipients with graft survival > 6 months, DDLTs had a slower decline in eGFR as compared to LDLTs (p < 0.01). Among LDLTs, the decline in eGFR continued over the entire 10-year period, whereas among DDLTs, the decline in eGFR slowed significantly after six months (p = 0.01). more


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