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Somatic mosaic mutations in ovarian cancer linked to chemotherapy exposure, age

from Healio

Factors such as older age and chemotherapy receipt appeared associated with somatic mosaic mutations in women with ovarian cancer, according to study results published in JAMA Oncology. Somatic mosaic mutations in the p53-inducible protein phosphatase gene PPM1D have been observed in the peripheral blood mononuclear cells of patients with breast cancer, lung cancer and ovarian cancer, according to study background. However, no cause or effect has been determined. more


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