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HLA-incompatible kidney donation may increase survival compared to waiting

from 2 Minute Medicine

Given the limited resource of organs for kidney transplant, there have been numerous efforts, including accepting kidneys from expanded criteria donors, to increase available organs. One strategy for recipients is to undergo desensitization and accept a kidney graft from a human leukocyte antigen incompatible live donor as opposed to remaining on the transplant waiting list. Given that patients with anti-HLA antibodies may remain on the waiting list without a suitable donor ever being identified, receiving an HLA-incompatible graft may provide better outcomes than waiting. This study aimed to determine the effect of transplantation with kidneys from incompatible live donors on survival as compared to matched controls who remained on the transplant waiting list or those who waited on the transplant list for decreased donor grafts. more

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