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Spectrum of anemia after kidney transplantation: Pathophysiology and therapeutic implications

from Clinical Transplantation (login required)

The prevalence of anemia in the first month after transplant is 70 percent–80 percent. The rate declines to 30 percent–40 percent at 3 months and 20 percent by 12 months. Its occurrence is influenced by the quality of the transplanted organ, bone marrow regenerative capacity, amount of surgical blood loss, and increased iron recycling. There is also a blunted response by oxidative inflammation to the effectiveness of supranormal levels of erythropoietin (EPO) release during ischemic-reperfusion allograft injury. more

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