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Where cells go: Mechanical and chemical cues collaborate to guide them

from Johns Hopkins Medicine via ScienceDaily

Living cells respond to biochemical signals by moving toward those at higher concentration, a process carefully mapped out by biologists over the past several decades. But cells also move in response to mechanical forces, such as bumping up against other objects — although the details of that action have been poorly understood. Now, results of a new study, published Nov. 7 in the journal PNAS, reveal that cells use the same network of molecules to react to both chemical and mechanical signals, allowing them to combine potentially conflicting signals into a unified path. more


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