From Name:
From Email:
To Name:
To Email:

Optional Message:

R01 Opportunity: Circadian mechanisms contributing to obesity, diabetes metabolism and underlying heart, lung and blood disorders

from National Institutes of Health

This FOA invites clinical research applications to elucidate circadian-dependent mechanisms contributing to the pathophysiology of human obesity, diabetes-related metabolism, obesity-coupled risks for heart, lung, and blood disease, and the identification of novel therapies to improve circadian rhythm for primary or secondary prevention and management of obesity-associated disease risks. Mechanistic clinical studies to elucidate the relationship of circadian rhythm to causal pathways of disease are encouraged. Intervention studies to identify circadian-mediated mechanisms of obesity, diabetes-related metabolism, and obesity-coupled heart, lung, and blood pathophysiology may be proposed. Behavioral, physiological, pharmacological, molecular, and genomic studies aimed at elucidating the relationship between circadian-dependent mechanisms and disease are appropriate. Multidisciplinary, multiple investigator teams are strongly encouraged to realize the full potential for synergy between experts in heart, lung, blood, and metabolic disorders with circadian and sleep researchers. Studies of epidemiological risk and clinical trials to assess therapeutic efficacy, effectiveness, or implementation are outside the scope of this program.

Applications are due by March 14, 2017. Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date. Find out more and apply online. more

Powered by MultiBriefs
7701 Las Colinas Blvd., Ste. 800, Irving, TX 75063