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Breast cancer study finds 72 new genetic risk variants

from Genetic Engineering & Biotechnology News

An international research consortium has identified 72 new gene variants that predispose to breast cancer, through an analysis of genetic data from more than 275,000 women. Many of the variants lie in regulatory, rather than coding regions, and and additional seven are specific for estrogen receptor-negative breast cancer. The OncoArray consortium hopes that the findings from their genome-wide association studies will provide new insights into the genetic basis of breast cancer, as well as open up new avenues for research into early diagnosis, treatment, and potentially prevention of breast cancer, particularly for hormone therapy–resistant, ER-negative disease. more

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