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Stem cell subset source of all blood cells, basis of bone marrow transplant success

from Genetic Engineering & Biotechnology News

A new blood system isn’t created from scratch — just something close to it. A single type of stem cell, a new study demonstrates, can fully repopulate the bone marrow and give rise to all the cell lineages that constitute a complete blood system. This blood-forming stem cell is distinguished by three cell-surface markers — or rather the presence of two markers and the absence of a third. By heeding these markers, scientists may improve transplantation procedures, as well develop better gene therapy and gene-editing approaches. more

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