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Association of quantitative metastatic lymph node burden with survival in hypopharyngeal and laryngeal cancer

from The JAMA Network

Greater incorporation of numerical metastatic nodal burden into nodal classification for hypopharyngeal and laryngeal cancers may streamline staging, refine patient prognosis and triage patients who may benefit from adjuvant treatment. Nodal staging for laryngohypopharyngeal cancers is based primarily on size and laterality, with less value placed on absolute number of metastatic lymph nodes (LNs). We are aware of no studies to date that have specifically addressed the prognostic effect of quantitative nodal burden in larynx or hypopharynx malignancies. more

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