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Targeted fluorescence successfully identifies pulmonary metastases in osteosarcoma patient

from The Medical News

In a proof-of-principle case report, researchers announce that targeted fluorescence successfully identified pulmonary metastases in a patient with osteosarcoma, making it easier for surgeons to locate the tumors for resection. Osteosarcomas express a number of unique molecular markers, including the folate receptor alpha. In this study, the fluorescence emitted from the contrast agent allowed surgeons to locate both a known lung nodule and a small occult metastases — less than a half a centimeter — that was not visible in preoperative imaging, suggesting that this approach may enable the detection of small or hard-to-locate nodules during minimally invasive resection. more

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