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New paper suggests that tumor cells may develop resistance to potential RAS inhibitors

from Medical Xpress

Researchers have long sought a treatment aimed specifically at the RAS family of genes, the most common oncogenes and those that initiate many of the most lethal tumors. However, the results of a hypothetical treatment may be far less positive than speculated, according to a manuscript published in Genes & Development by the Genomic Instability Group at the Spanish National Cancer Research Centre. The study shows that cells are capable of surviving even in the total absence of RAS genes if another gene, Erf, is also lost. more

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