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NOACs Carry Lower MI Risk Versus Warfarin in Real-world Study

from TCTMD

The risk of myocardial infarction is lower in patients with atrial fibrillation starting treatment with a direct nonvitamin K antagonist oral anticoagulant rather than a vitamin K antagonist (VKA) for stroke prevention, Danish researchers report, adding fodder to a debate about MI risks that has been ongoing since the RE-LY trial results were first reported back in 2009. Overall, the standardized risk of MI in the year after initiating treatment was 1.1 percent to 1.2 percent with dabigatran, rivaroxaban and apixaban and 1.6 percent with a VKA, with lower absolute risks of 0.4 percent to 0.5 percent with the newer agents, according to Christina Ji-Young Lee, MD, and colleagues. more


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