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Function of T regulatory type 1 cells is down-regulated and is associated with the clinical presentation of coronary artery disease

from Human Immunology

T regulatory type 1 (Tr1) cells can promote tolerance and suppress inflammation. Atherosclerosis may be induced by the proinflammatory activation of cells in the vasculature and the immune system. Hence, we wondered whether defects in Tr1 function were a contributing factor to coronary artery disease (CAD). more

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