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Keeping up with testing guidelines in lung cancer

from Archives of Pathology & Laboratory Medicine

The evaluation of lung carcinoma, especially lung adenocarcinoma, has undergone a radical change centered on molecular alterations that predict treatment response. Because these molecular alterations activate important oncogenic pathways, blockade provides a targeted approach to tumor therapy. As a result of this pairing of molecular event and therapy, tumors that harbor the alteration may be particularly responsive to a focused intervention, whereas those that do not are either less responsive or nonresponsive. more

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