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A rare genetic aversion to sweets could be key to fighting obesity

from Bloomberg

For a lucky few people in the world, weight will never be a source of worry. People who have a rare genetic mutation called essential fructosuria lack the primary enzyme needed to metabolize fructose, a natural sugar found in honey, fruits and vegetables. No ill consequences have been linked to the defect, save for an aversion to sweets, and it appears to have a significant benefit: Those who have it seem to be at little risk of obesity, type 2 diabetes or serious liver ailments. more


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