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Study points toward new strategies for managing organ transplantation

from News-Medical

The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found. Scientists had previously thought that blood cells are created exclusively in the bone marrow from a special population of hematopoietic stem cells. Intestinal transplantation is the only long-term option for patients with Crohn's and other diseases if their intestines fail. But high rejection rates and life-threatening complications from immunosuppression have limited the success of human intestinal transplantation. more


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