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Tailored Treatment of Patients With Hepatocellular Carcinoma With Portal Vein Invasion: Experience From a Multidisciplinary Hepatobiliary Tumor Program Within a NCI Comprehensive Cancer Center

from Journal of Gastrointestinal Oncology

BACKGROUND: Hepatocellular carcinoma (HCC) with portal vein invasion (PVI) has a poor prognosis with limited treatment options. Intra-arterial brachytherapy (IAB) and transarterial chemoembolization (TACE) yield local control but risk accelerating liver dysfunction. The outcomes, survival, and safety of selective liver-directed treatment are reported. METHODS: Thirty-seven consecutive patients with HCC and PVI treated between 2009 and 2015 were reviewed from a prospectively collected database. more


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