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The Expanding Spectrum of Antibody-Mediated Rejection: Should We Include Cases Where No Anti-HLA Donor-Specific Antibody Is Detected?

from American Journal of Transplantation

Antibody-mediated rejection (ABMR) in a renal transplant biopsy is most often diagnosed by a combination of microvascular injury (MVI), C4d deposition, and presence of circulating DSA. MVI designates the leukocyte margination reaction in glomeruli (glomerulitis, Banff score g) and in peritubular capillaries (peritubular capillaritis, Banff score ptc). more

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