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Fluorescing Urine Signifies Organ Transplant Rejection, Could Replace Needle Biopsies

from ECN

Too often, it's only after a transplanted organ has sustained serious damage that a biopsy reveals the organ is in rejection. A new screening method using sensor particles and a urine test could catch rejection much earlier, more comprehensively, and without a biopsy needle. When the body's immune system has just begun attacking cells of a transplanted organ, the new method's particles send a fluorescent signal into the urine. In a new study, researchers at the Georgia Institute of Technology and Emory University validated the method in a mouse model, and they have engineered the sensor with highly biocompatible components, which could make the path to potential future trials easier. more


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