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A Randomized Trial of Everolimus-Based Quadruple Therapy Vs Standard Triple Therapy Early After Lung Transplantation

from American Society of Transplant Surgeons via Wiley Online Library

Calcineurin inhibitor therapy after lung transplantation increases risk of kidney failure. Early everolimus-based quadruple low CNI immunosuppression may improve renal function without compromising efficacy or safety. A prospective, randomized, open-label, 12-month multicenter trial was conducted at eight German sites. Patients three to 18 months after transplantation were randomized. more


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