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Improving Our Mechanistic Understanding of the Indirect Effects of CMV Infection in Transplant Recipients

from American Journal of Transplantation

CMV is an immunomodulatory virus that indirectly increases the risk for bacterial, fungal and viral infections. However, the pathogenesis of this phenomenon is poorly understood. We determined whether inflammatory responses to different Toll-like receptor (TLR) ligands are blunted during CMV infection in solid organ transplant (SOT) patients. more

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