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Signs, portents and immuno-oncology biomarkers

from Genetic Engineering & Biotechnology News

When translational researchers, drug developers and clinical scientists seek immuno-oncology foresight, they often find it in biomarkers — or better still, the patterns formed by multiple biomarkers. Single biomarkers convey little of cancer's complexity, leaving much unclear about the signaling pathways that sustain or suppress malignancies, the mechanisms that activate or deactivate specific immune defenses, or the contingencies that culminate in "hot" or "cold" tumor microenvironments. more

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